Clinical Applications: Anticoagulant Testing

Keeping Blood Clots at Bay: More Patients at Risk

Anticoagulants are used when patients are at risk of developing blood clots that could potentially block a blood vessel and disrupt the flow of blood around the body. These blood clots can cause stroke, heart attack, deep vein thrombosis (DVT) or pulmonary embolisms (PE). Each year more than 15 million people suffer strokes worldwide, while many more are diagnosed with blood clots prior to an event, posing a large economic burden on healthcare systems in developed countries.

Besides a steady increase in anticoagulant use by a growing number of organic bood clot patients, anticoagulant use has also jumped due to increasing orthopedic surgery such as elective knee or hip replacement, where venous thromboembolisms (VTEs) must be prevented following the operation.

Some of the most commonly used anticoagulant medications to help prevent clotting, such as warfarin (commercial name Coumarin®), interact with other medications and even some foods, altering effectiveness. This means that anticoagulant status and dosage must be carefully monitored through blood testing. Traditionally this testing was carried out by sending samples to a hospital based or central lab.

With the advent of point-of-care (POC) and home testing systems such as Micropoint’s microfluidics-based qLabs® handheld device, healthcare teams or patients can obtain PT/INR results in just 2 minutes, streamlining the testing process, keeping costs low, and enabling patients to maintain their quality of life following a diagnosis of blood clot risk. The company’s Coag Panel 2 cartridge, a 2-in-1 solution, allows medical teams to test for both PT/INR and aPTT at the same time in less than 7 minutes. Micropoint’s mLabs® D-Dimer test helps check for VTE and can help doctors assess DVT or PE status.

Disease

Stroke  

Strokes occur when something happens to interrupt the flow of blood to brain cells, such as a blood clot, and they no longer can get oxygen. A stroke can cause lasting brain damage, long-term disability, or even death.

Myocardial Infarction (MI)

A myocardial infarction, or heart attack, occurs when a part of the heart muscle doesn’t receive enough blood flow. The more time that passes without treatment to restore blood flow, the greater the damage to the heart muscle.

Venous Thromboembolisms (blood clots)

Pulmonary Embolism (PE) 

A pulmonary embolism is a blockage in one of the pulmonary arteries in your lungs. In most cases, pulmonary embolism is caused by blood clots that travel to the lungs from the legs.
 

Deep Vein Thrombosis (DVT)

Deep vein thrombosis occurs when a blood clot (thrombus) forms in one or more of the deep veins in your body, usually in your legs. Deep vein thrombosis can cause leg pain or swelling, but may occur without any symptoms.

Micropoint POC Test

qLabs PT/INR, qLabs aPTT

qLabs PT/INR, qLabs aPTT

mLabs D-Dimer

mLabs D-Dimer

Clinical Application

  • Blood testing to ascertain effectiveness and dosage of anticoagulant Warfarin (Coumadin   )

  • Blood testing to ascertain effectiveness and dosage of anticoagulant Warfarin (Coumadin   )

 

  • Early diagnosis and post-clot assessment

  • Early diagnosis and post-clot assessment

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