Clinical Applications: Infection

Sepsis and severe bacterial infection on the rise and under-recognized

Sepsis, which is often misunderstood by the public as “blood-poisoning” is one of the leading causes of death around the world. Sepsis arises when the body’s response to an infection injures its own tissues and organs. It may lead to shock, multiple organ failure, and death, especially if not recognized early and treated promptly. Between one third and one half of patients with sepsis die. According to the Global Sepsis Alliance, an estimated 20 – 30 million cases of sepsis occur worldwide each year. New research indicates that in the last decade, gram-positive bacteria -- most commonly staphylococci -- are thought to have caused more than 50% of cases of sepsis.

The Alliance estimates that $14.6 billion was spent on hospitalizations for sepsis in the US in 2008, and from 1997 through 2008, the inflation-adjusted aggregate costs for treating patients hospitalized for this condition increased on average annually by 11.9%. The costs related to long-term sequelae of sepsis are unknown. In Europe, it has been estimated that a typical episode of sepsis costs healthcare services approximately 25,000 Euros. Given the considerable loss of life years the human costs of sepsis are enormous.

A one-hour treatment window

Traditionally,  identification of pathogens in bloodstream infections required culturing patient blood in an automated continuous monitoring system followed by Gram stain and sub-culturing, a process that can take up to 72 hours. Every hour that appropriate treatment is delayed has been shown to increase mortality by 7%. Guidelines for the Surviving Sepsis Campaign 2012 recommends administration of broad-spectrum antimicrobial therapy within one hour of septic shock recognition

 

Micropoint offers significant time savings

Micropoint's mLabs® PCT test at point-of-care provides medical teams with the ability to evaluate and differentiate infection types within 8 minutes, providing medical teams with a significantly earlier diagnosis and higher chances for improved outcomes than using standard lab practices. 

Disease

Sepsis

Sepsis is a life-threatening condition that arises when the body's response to infection injures its own tissues and organs.

Clinical Application

  • Rapid evaluation for bacterial infection and sepsis

  • Differentiate inflammatory reaction from bacterial infection

Micropoint POC Test

 

mLabs PCT

 

 

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